Author

John Cade; Jean Delay, Pierre Deniker and J.-M. Harl; Roland Kuhn

About John Cade; Jean Delay, Pierre Deniker and J.-M. Harl; Roland Kuhn

John Cade (1912–1980) was an Australian psychiatrist and former prisoner of war. Jean Delay (1907–1987) and Pierre Deniker (1917–1998) were psychiatrists at the Sainte-Anne Hospital in Paris. Roland Kuhn (1912–2005) was a Swiss psychiatrist at the cantonal asylum of Münsterlingen on Lake Constance. Their reports introduced the first effective drug treatments for mania, psychosis and depression.

On this site

Founding Papers of Psychopharmacology: Cade on Lithium (1949), Delay, Deniker and Harl on Chlorpromazine (1952), Kuhn on Imipramine (1957)

1949–1957 · Postwar Contemporary · Essays

This record brings together three short clinical papers that began the modern era of drug treatment in psychiatry. Before them, patients with severe mental illness were often confined for years in crowded hospitals, and the available physical treatments, such as sedation, insulin coma and electroconvulsive therapy, were limited or dangerous.