Author

Frederick G. Banting and Charles H. Best

About Frederick G. Banting and Charles H. Best

Frederick Banting (1891–1941) was a Canadian surgeon and First World War veteran; Charles Best (1899–1978) was a University of Toronto student who became his assistant in the summer of 1921 and later a leading physiologist. Working in J. J. R. Macleod's laboratory, with help from the biochemist James Collip, they isolated insulin.

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The Internal Secretion of the Pancreas

1922 · Early 20th Century · Essays

'The Internal Secretion of the Pancreas' is the first scientific paper describing the work at the University of Toronto that led to insulin. Frederick Banting and Charles Best presented their results to a physiological society in Toronto in late 1921, and the paper was published in the Journal of Laboratory and Clinical Medicine in February 1922.